Research

P. Nagarajan

B.Vet .Sci, M. Sc.

Tamil Nadu Veterinary and Animal Science University

FELESA Certificate course in Laboratory Animals –Utrecht University

Postdoctoral Research
National University of Singapore

Email
nagarajan@nii.ac.in

 

Research Interest

Laboratory animals, Animal models, Metabolic Disease

Summary of Research

My major activities include care, breeding and health of laboratory animals used in research. Other area of interest includes the study on animal models for metabolic syndrome and related diseases.

Selected Publications

  • Alaknanda Mishra, Barun Das, Madhu Nath, Srikanth Iyer, Ashwani Kesarwani, Jashdeep Bhattacharjee, Shailendra Arindkar, Preeti Sahay, Kshama Jain, Parul Sahu, Prakriti Sinha, Thirumurthy Velpandian, Perumal Nagarajan, Pramod Upadhyay Novel immunodeficient Pde6b rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration. Biology Open 2017: doi: 10.1242/bio.021618.
  • Baligar P, Kochat 1, Arindkar SK, Equbal Z, Mukherjee S, Patel S1, Nagarajan Perumal, Mohanty S, Teckman JH, Mukhopadhyay A. Bone marrow stem cell therapy partially ameliorates pathological consequences in livers of mice expressing mutant human α1-antitrypsin. Hepatology. 2017 Apr;65(4):1319-1335.
  • Shajahan A, Parashar S, Goswami S, Ahmed SM, Perumal Nagarajan,  Sampathkumar SG. Carbohydrate-neuroactive hybrid strategy for the metabolic glycan engineering of the central nervous system in vivo. J Am Chem Soc. 2016 Dec 20
  • Mishra A, Upadhyay PK, Nagarajan Perumal . Immunotherapy in Liver Diseases: A Balance Between Immunity and Tolerance. Curr Drug Metab. 2016 Nov 16. 
  • Mishra A, Iyer S, Kesarwani A, Baligar P, Arya SP, Arindkar S, Kumar MJ, Upadhyay P, Majumdar SS, Nagarajan Perumal *.  Role of antigen presenting cell invariant chain in the development of hepatic steatosis in mouse model. Exp Cell Res. 2016 Jun 28
  • Bhattacharjee J, Das B, Sharma D, Sahay P, Jain K, Mishra A, Iyer S, Nagpal P, Scaria V, Nagarajan P, Khanduri P, Mukhopadhyay A, Upadhyay P. Autologous NeoHep Derived From Chronic Hepatitis B Virus Patients' Blood Monocytes by Upregulation of cMET Signaling. Stem Cells Transl Med. 2016 Jul 28.
  • Srikanth Iyer, Pramod Kumar Upadhyay, Subeer S. Majumdar, Perumal Nagarajan * .Animal Models Correlating Immune Cells for the Development of NAFLD/NASH. In Press  Journal of clinical and Experimental hepatology 
  • Kochat V, Kanjirakkuzhiyil S, Baligar P, Nagarajan Perumal, Mukhopadhyay A. Donor antigen-primed regulatory T cells permit liver regeneration and phenotype correction in hemophilia A mouse by allogeneic bone marrow stem cells. Stem Cell Res Ther. 2015 Jul 8;6(1):129. 
  • Srikanth Iyer, Shailendra Arindkar, Alaknanda Mishra, Kapil Manglani, Jerald Mahesh Kumar, Subeer S Majumdar, Pramod Upadhyay and Perumal Nagarajan *  Development and evaluation of transgenic nude mice expressing ubiquitous green fluorescent protein (2015 [Molecular Imaging & Biology 2015 Aug;17(4):471-8.

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